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This pro-angiogenic effect involves stimulation of vascular endothelial growth factor (VEGF) production and activation of endothelial cells to proliferate, migrate, and form new capillary networks

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Although BBB protects the brain by prohibiting toxic substances from entering into the brain parenchyma, it also limits the entry of anti-PD nanomaterials, rendering these nanomaterials inefficient [16, 17]

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Hence, the idea for this study arose, and we hope that the results of this study will be used to develop pharmaceutical formulations of safflower to treat these diseases and alleviate pain

Modulation of the gut microbiota and glycometabolism by a probiotic to alleviate amyloid accumulation and cognitive impairments in AD rats